Bioecology is individual environmental information relating to an individual's life in order to grow and develop in the environment or suitable habitat. It is a major requirement that must be known before applying the concept of an integrated disease control. The information of bioecology played as a major factors that can be used to suppress the growth of pathogens, so that will not cause any harm and damage to crops. Tidal swampland with four different types of tipology (tipology A, B, C, and D), has different characterize of bioecology, so the existence of microbes in that tipology will also be different. The use of nonpathogenic Fusarium (NPF) that specific location of tidal swampland as biological control agents has not been done. Nonpathogenic fusarium is able to reside in the plant for a long time without causing any harm to the plant. It is expected to protect plants from pathogens interference in tidal swampland continuously. The research aims to gain information in order to exploit the NPF as biological control agents through determining it bioecology and it ability to protect rice plants against harmful pathogens Fusarium wilt. It is expected that NPF could become biological control as an integral part of sustainable farming systems in tidal swampland.The results showed that the intensity of Fusarium wilt disease was higher in the rainy season in the typology A, B and C, while in typology intensity of Fusarium wilt disease high in the dry season. FNP growth assay in vitro depends on: the temperature (25-30oC) and pH (6.5 to 7.5). FNP can be distinguished from Fusarium pathogens based on colony color and growth, makrokonidia diameter, speed of growth in the media, and the power of the antagonist. The test results proved that in in-vivo test, antagonist of FNP whichapplicated through the soil a week before planting with a dose formulations 30 kg/ha was quite high (over 80%). while the aplication in soaking seeds in spore density of 106 for 24 hours before planting, resulted better in inhibiting the progression of the disease (above 90%). The ability of FNP to suppress disease found better than the synthetic fungicide. It appears that the power intensity of the disease result in antagonists FNP only ranged from 19.68% -27.55%, while the intensity of the disease in fungicides aplication as much as 53.36%. Keywords: Bioecology, Nonpathogenic Fusarium, tidal swampland.