Abstract:
Cataracts are opacities of the eye lens that occur due to degenerative processes and diabetes
mellitus (DM). The circumstances cause an increase in free radicals and a decrease in antioxidant activity
until oxidative stress occurs. This research aims to compare the activity of superoxide dismutase (SOD)
and catalase enzymes in cataract lenses with DM and non-DM patients. The subjects of the study were
cataract lenses that were taken when subjects underwent cataract surgery by phacoemulsification method.
The research subjects were divided into 2 groups:15 people with DM and 15 non-DM people. The results of
the statistical test using the Mann-Whitney test with a confidence level of 95% showed p = 0,000, so it can
be concluded that there were significant differences between the average activity of SOD and catalase
enzymes in cataract lenses of DM and non-DM patients.
Keywords: cataract, diabetes mellitus, oxidative stress, superoxide dismutase enzyme
