Abstract The effect of ethanolic extract of Morinda citrifolia leaves and fruit on blood pressure in dexamethasone-induced hypertension rat was evaluated. Total phenolic content of Morinda citrifolia leaves ethanolic extract (MCLEE) and Morinda citrifolia leaves ethanolic extract (MCFEE) was 1.789+0.116 and 1.677+0.051 mg of gallic acid equivalents per gram sample, respectively. Rutin level in MCLEE was 0.92 + 0.19%, and scopoletin level in MCFEE was 0.46 + 0.05%. MCLEE, MCFEE, and its extract combination significantly decreased the blood pressure of hypertensive rats. The combination group showed highest hypotensive activity by lowering systolic blood pressure by 16.71+3.95%, diastolic blood pressure by 21.49+7.90%, and mean arterial blood pressure by 19.58% + 6.35. All extract treatments have not been able to repair or inhibit renal damage caused by dexamethasone induction.