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Hypotensive Activity of Ethanolic Extracts of Morinda citrifolia L. Leaves and Fruit in Dexamethasone-Induced Hypertensive Rat

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dc.creator Anwar, Khoerul
dc.date.accessioned 2020-06-15T03:59:27Z
dc.date.available 2020-06-15T03:59:27Z
dc.identifier http://eprints.ulm.ac.id/3045/1/JEBCAM_Dyan_Compressed.pdf
dc.identifier Anwar, Khoerul Hypotensive Activity of Ethanolic Extracts of Morinda citrifolia L. Leaves and Fruit in Dexamethasone-Induced Hypertensive Rat. Journal of Evidence-Based Complementary & Alternative Medicine. ISSN DOI: 10.1177/2156587216653660
dc.identifier.uri https://repo-dosen.ulm.ac.id//handle/123456789/11284
dc.description Abstract The effect of ethanolic extract of Morinda citrifolia leaves and fruit on blood pressure in dexamethasone-induced hypertension rat was evaluated. Total phenolic content of Morinda citrifolia leaves ethanolic extract (MCLEE) and Morinda citrifolia leaves ethanolic extract (MCFEE) was 1.789+0.116 and 1.677+0.051 mg of gallic acid equivalents per gram sample, respectively. Rutin level in MCLEE was 0.92 + 0.19%, and scopoletin level in MCFEE was 0.46 + 0.05%. MCLEE, MCFEE, and its extract combination significantly decreased the blood pressure of hypertensive rats. The combination group showed highest hypotensive activity by lowering systolic blood pressure by 16.71+3.95%, diastolic blood pressure by 21.49+7.90%, and mean arterial blood pressure by 19.58% + 6.35. All extract treatments have not been able to repair or inhibit renal damage caused by dexamethasone induction.
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dc.relation http://journals.sagepub.com/doi/full/10.1177/2156587216653660
dc.relation http://eprints.ulm.ac.id/3045/
dc.subject AI Indexes (General)
dc.title Hypotensive Activity of Ethanolic Extracts of Morinda citrifolia L. Leaves and Fruit in Dexamethasone-Induced Hypertensive Rat
dc.type Article
dc.type PeerReviewed


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