Tidal swamps are mostly cultivated with by local paddy varieties and one of the plant diseases that is very crucial in transplanting stage (taradak, ampak and lacak) is soil borne pathogen. The research was conducted on tidal swamps type B in Barito Kuala, South Kalimantan, it was M&M arranged in split plot design with the combination of endophytic microbe and transplanting stage application time as the treatments. Endophytic microbes formulation were Trichoderma viride PS-2.1, Nonpathogenic Fusarium PS-1.5, and Pseudomonas fluorescens PS-4.8. Combination application of endophytic microbes and transplanting stage on tidal swamps could decrease the disease intensity of sheath blight, as about 49.39 to 93.25%. Endophyte could also be able to stimulatethe plant growth that was indicated by the addition of plant height around 2.05 to 24.00 cm, the addition of rice grain weight as 0.7 to 9.3 g/1000 grains, and the addition of seed weight as about 0.3-1.2 kg. The result of soil analysis before and after application the endophyte showed that there was an increase in soil fertility with the element addition of N, P, K and pH.