Abstract:
Several investigations are extensively documenting the presence of metabolites with antibacterial,
anticancer, antioxidant, and anti-inflammatory properties in extracts derived from Rhodomyrtus tomentosa fruits
and leaves. Therefore, this study aimed to evaluate the metabolite profile of R. tomentosa fruits and leaves at
various maturity stages and determine their phytomedicinal values. 1H NMR and chemometric analyses were
used to conduct a metabolomics study for comparing the metabolite profile and phytomedicinal values of
different plant organs at varying ages. Leaves were classified into young and old categories, while fruits were
divided into three maturity stages, namely green, red, and purple. The wild-grown fruits and leaves of R.
tomentosa (Ait.) Hassk were gathered in Banjarbaru, South Kalimantan Province, Indonesia. The results of
multivariate analysis showed that choline, methionine, mannitol, and β-glucose compounds were three times
higher in fruits compared to leaves. Meanwhile, the concentration of aspartate, myricetin, and quercetin
compounds was three times higher in leaves compared to fruits. The quantities of secondary metabolites,
including flavonoids, were higher in young leaves and green fruits than in old, red, and purple fruits.
