Abstract:
This study aimed to isolate and characterize compounds from the distillation residue of cinnamon oil from
Loksado, South Kalimantan. Cinnamon (Cinnamomum burmanii) distillation residue was extracted with
methanol as solvent. The methanol extract was fractionated by liquid vacuum chromatography to obtain
fractions A, B, C, and D. The crystals contained in fraction C were washed with cold n-hexane to obtain 5.4
mg of yellow isolate (FC1). FC1 isolates were characterized by UV-Vis, IR, 1H-NMR, and 13C-NMR
spectrophotometers. UV spectra showed a maximum wavelength at 307, 316, and 321 nm indicating the
presence of a conjugated or aromatic system. The infrared spectra showed -C=O, -OH, C-O, C-H, C-N, and
C=N groups. The 1H-NMR spectra showed the presence of aromatic protons at 6.38 ppm (1H, d, J=9.5 Hz),
7.67 ppm (1H, d, J=9.5 Hz), 7.29 ppm (1H, d, J=8 Hz), 7.44 ppm (1H, d, J=8 Hz), and 7.49 ppm (1H, t)
and there was a methyl proton (acetyl group) at H 2.13 ppm (3H,s). The 13C-NMR spectra showed the
presence of a C=O ketone group at 207.26 ppm and there were 9 C-sp2
at 116.9; 119.0;124.6;
128.1;132.0;143.7; 154.3; 161.0 ppm, which δC 161.0 ppm was C-oxyaryl. Based on UV, IR, 1H and 13CNMR spectra data, FC1 isolate was suggested as an isoquinoline alkaloid substituted by OH and acetyl
groups.
Keywords: distillation residu, Cinnamomum burmanii, alkaloid, isoquinoline.
