Abstract:
Panoramic radiography is a radiographic diagnostic tool that affects the Reactive Oxygen
Species and causes oxidative stress, which has a role in DNA damage that occurs due to
periodontitis or panoramic radiographic radiation exposure is characterized by the formation
of micronuclei in gingival epithelial cells. Panoramic radiography exposure and periodontitis
can increase the Gingival Crevicular Fluid (GCF) flow because of increased vascular
permeability. The present study aims to determine the effect of panoramic radiography on the
volume of GCF and micronuclei in Wistar rats with periodontitis. This study was true
experimental with post-test only and control group design, used 40 male Wistar rats. The
average number of GCF in the healthy rats' group that was not exposed to panoramic
radiography was 0.114 μL, the periodontitis rats group that was not exposed, once, twice, and
three times exposed to panoramic radiography were 0.246, 0.286, 0.294, and 0.374 μL,
respectively. The result of the One-Way Annova test and Post Hoc Bonferroni test indicated
that significant changes in the number of micronuclei were seen between the normal group
with once exposure to the periodontitis group with two times and three times exposure and in
the periodontitis group without exposure to the periodontitis group with two times and three
times exposure. Panoramic radiograph X-ray radiation causes an increase in the volume of
GCF and changes the number of micronuclei in Wistar rats with periodontitis.
Keywords: panoramic radiography, Gingival Crevicular Fluid, micronucleus, periodontiti.
