Abstract:
Blood leukocyte differentiation is one parameter to determine the health status of the animals,
because of the differentiation of blood leukocytes is a component that has an important function
as the body's first defense when disease or foreign substances into the body. Katuk is a medicinal
plant that has several active substances that serve to health. This study aims to determine the
leukocyte differentiation from sheep given the leaf extract fraction katuk. Complete randomized
design (CRD) was used with 4 replications and 4 treatments fraction katuk leaf extract. The
treatments include: control, Ethanol crude extract (1500 mg / day of extract ETOH), delipidasi
fraction (1230 mg / day FDL) and hexane fraction (270mg / day FH). Fractions katuk leaf extract
given to sheep in capsule form that is 2 times a day for 2 months. Leukocyte differentiation
calculation performed after 2 months of treatment. The results show that the value of leukocyte
differentiation sheep after administration leaf extract fraction katuk namely lymphocytes,
neutrophils, monocytes, eosinophil and the sequence is (41.5-46)%, (47.7-54,7)%, ( 1.5-2.7)%,
(2.2-6)%. Leukocyte differentiation value in this research is still in the normal range sheep. This
shows that the treatment of fraction katuk leaf extract does not interfere with physiological health
status of sheep.
Keywords: leukocytes, katuk leaves, sheep
