Abstract:
Abstract:Peritoneal insufflation is swelling process to perform laparoscopic surgery, the choice of gas for insufflation in laparoscopic surgery, namely CO2. because it is not flammable bleak N2O, so it can be used safely for diathermy in mice. This study aims to determine whether there is influence insufflation in an increased number of mast cells in rats (Rattus norvegicus). This study is pure experimental research with posttest-only control group design, which consists of the control and treatment of pressure 8 mmHg and 10 mmHg, with the results obtained p0 control = 0.52 p1 8 mmHg = 7.84 p2 10 mmHg = 11.94. ANOVA test showed that the increase in the number of mast cells was significantly occurred in the group with a pressure of 10 mmHg as compared to the pressure of 8 mmHg. Based on research carried out can be concluded that the higher the CO2 gas in the insufflation pressure significantly increases the number of mast cells.
