"This research was aimed to explain about operculum movement and microanatomy skin structure of P. schlosseri with interval calculation of oxygen uptake by operculum while P. schlosseri stay on the land and undergo skin preparation to observe part of skin and mucous cell microscopically. Sampling was conducted by using the endangered animal catching method with line transect. The observation of operculum movement was done using camera video or direct observation. The observation of skin microanatomy was done using paraffin method and then observed under the microscope. The result of this research showed that average of interval oxygen uptake is 7.25 minute. The result shows that mucous cell is on skin layer of P. schlosseri found in epidermis layer with average range between mucous cell equal to 16.96 m and average broad size is 73.87 m."