Based on field observations, ethnic Bugis Pagatan has been using medicinal herbs for health and other uses for the past. Society generally derives knowledge from oral tradition. Until now, data and information on utilization based on local wisdom is not yet available and well documented. This raises concerns about the extinction of traditional knowledge in the utilization of plants. This research was conducted on Bugis Pagatan community in Kusan Hilir Subdistrict, Tanah Bumbu Regency. The objectives of the study were to (1) identify the types of medicinal plants utilized by the ethnic Bugis Pagatan and (2) to identify 5 (five) types of medicinal plants utilized by the Bugis Pagatan community based on local wisdom. Data collection is done by interviewing the local community of Bugis Pagatan ethnic who know the benefits of plants as a medicine. The technique of selecting the informant as the research sample used in this research phase is by purposive sampling and snowball sampling method. Interviews aimed at traditional healers (sanro). Each medicinal plant is recorded in its local name, the part used, and how it is used and its use. This study obtained 49 (forty nine) kinds of medicinal plants used by the community, and 5 (five) types of medicinal plants based on local wisdom ie (1) Aju Jawa (Lannea coromandelica Linn.), (2) Allere (Ipomoea pes-caprae Sweet.), (3) Bujolo (Scaevola taccada (Gaertn.) Roxb.), (4) Paranga (Avicenia marina (Forssk.) Vierh.) And (5) Tawaro (Metroxylon sagu Rottb.).