| dc.creator |
Rahmawanty, Dina |
|
| dc.date.accessioned |
2020-06-15T03:57:18Z |
|
| dc.date.available |
2020-06-15T03:57:18Z |
|
| dc.identifier |
http://eprints.ulm.ac.id/1413/1/ABSTRACT_ISPST_DINA_RAHMAWANTY_revisi.pdf |
|
| dc.identifier |
Rahmawanty, Dina NANOPARTICLE PREPARATION AND CHARACTERIZATION OF HARUAN FISH (Channa striata) EXCTRACT CONTAINS ALBUMIN FROM SOUTH KALIMANTAN WITH IONIC GELATION METHOD. NANOPARTICLE PREPARATION AND CHARACTERIZATION OF HARUAN FISH (Channa striata) EXCTRACT CONTAINS ALBUMIN FROM SOUTH KALIMANTAN WITH IONIC GELATION METHOD. |
|
| dc.identifier.uri |
https://repo-dosen.ulm.ac.id//handle/123456789/9944 |
|
| dc.description |
ABSTRACT
Snakehead fish (Channa striata) has been reported to be used for wound healing by
people in South Borneo because it contains albumin. Snakehead fish extract (Channa
striata) has hydrophillic property and poor stability. Nanoparticle technology has
been started to be developed as an alternative solution to improve drug delivery
profile. The purpose of this study was to determine the formulation that obtained best
characterization for albumin nanoparticle. Albumin nanoparticles were prepared by
ionic gelation method, that was prepared by doing optimize ratio between snakehead
fish extract : chitosan and pH of chitosan solvent.Albumin nanoparticles were
characterized using Particle Size Analyzer for particle size and particle size
distribution, measurement of entrapment efficiency, determined Zeta potential using
Particle Size Analyzer, and observation of particle’s morphology using Transmission
Electron Microscope. The result showed that the chosen formula was formula 6
which ratio of extract : chitosan 1:2 with chitosan solvent pH 3, particle size 152.3
nm, polidispersity index 0.778, percentage of entrapment efficiency 51.3961 %, Zeta
potential +35.9 mV, and round shape of particles.
Keywords: ionic gelation, nanoparticle, snakehead fish (Channa striata) |
|
| dc.format |
text |
|
| dc.relation |
http://farmasi.unpad.ac.id/ispst2016/ |
|
| dc.relation |
http://eprints.ulm.ac.id/1413/ |
|
| dc.subject |
RS Pharmacy and materia medica |
|
| dc.title |
NANOPARTICLE PREPARATION AND CHARACTERIZATION OF
HARUAN FISH (Channa striata) EXCTRACT CONTAINS ALBUMIN FROM
SOUTH KALIMANTAN WITH IONIC GELATION METHOD |
|
| dc.type |
Article |
|
| dc.type |
PeerReviewed |
|