Diabetic Wound Healing Activity of Anabas testudineus Fish Scales

Abstract

Background:Anabas testudineusfish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation,produces chitosan. Chitosan is an efficacious compound forantibacterial anddiabetic wound healing.Objective:This study aimedto extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods:Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl,and 50% NaOH. FTIR will analyze the extraction resultsto see the functional groups of the extract. Activity test of fish scale extractsdia-betic wound healing gel was carried out on Rattus novergicusWistar strain for 14 days. There were five treatments:negative control, posi-tive control given octenillinR, and fish scale extract gel conc. 5%, 10%,and 15%.Results:The results showed that the fish scales extract contained chi-tosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%.Conclusion: A. testudineusfish scale extract contains chitosan,as seen from the FTIR results