Repo Dosen ULM

Dr. dr. M.Kes, M.Med.Ed

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dc.contributor.author Sanyoto, Didik Dwi
dc.date.accessioned 2024-06-04T06:22:22Z
dc.date.available 2024-06-04T06:22:22Z
dc.date.issued 2023-02-01
dc.identifier.issn 2774-2318
dc.identifier.uri https://repo-dosen.ulm.ac.id//handle/123456789/33774
dc.description.abstract Background: Stunting causes growth and development issues which are characterized by a systemic inflammatory response and neurotrans mitter disorder. Pasak Bumi (Eurycoma longifolia Jack) and seluang fish are abundant in South Kalimantan, and they are the potential to be ad junctive therapy for stunting management. Objective: To analyze the effect of Pasak Bumi extract (EPB) and selu ang fish administration in overcoming systemic inflammation and neu rotransmitter disorders in the stunting rats model. Methods: We used six groups of stunting rats: positive control (KP) group: placebo and standard diet, P1 group: 70% EPB 15 mg/kg body weight (BW) and standard diet; P2 group: DHA 1 mg/kg BW and stand ard diet; P3 group: EPB 15 mg/kg BW, DHA 1 mg/kg BW and stand ard diet; P4 group: seluang fish; P5 group: EPB 15 mg/kg BW and selu ang fish for fiveweeks; We measured levels of IL-6, TNF-α, and seroto nin. The data were analyzed by the ANOVA test with a 95% confidence interval. Results: The levels of TNF-α (p = <0.001) and serotonin (p < 0.001) were reduced significantly in the treatment groups. Conclusion: The administration of PBE and seluang fish was able to inhibit systemic inflammation and neurotransmitter dysregulation. en_US
dc.language.iso en en_US
dc.publisher Magna Medika Berkala Ilmiah Kedokteran dan Kesehatan en_US
dc.relation.ispartofseries 10;1
dc.subject stunting, seluang fish, pasak bumi, systemic inflammation, neurotransmitter en_US
dc.title Dr. dr. M.Kes, M.Med.Ed en_US
dc.title.alternative Effects of The Combination of Seluang Fish (Rasbora spp.) and Pasak Bumi (Eurycoma Longifolia Jack) on Systemic Inflammation and Neurotransmitter in Stunting Model Rat (Rattus Novergicus) en_US
dc.type Article en_US


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