Risk Factors of Hipertension and Diabetes Mellitus on COVID-19 Mortality

Abstract

Case fatality rate (CFR) for global COVID-19 infections since June 14, 2021 was 2.17%, while CFR for Southest Asia were 1.39%. CFR in Indonesia so far were 3.05%. This missed from the target of the 2005-2025 RPJMK (Middle long run national health planning) in achieving healthy Indonesia; handling epidemic diseases must be able to reduce the mortality rate below 1%. The government issued the Decree of the Minister of Health Republic of Indonesia No. HK.01.07/Menkes/2020 concerning the Determination of Vaccine Types for the Management of COVID-19. However, the existence of this policy did not reduce the mortality rate trend of COVID-19 in Indonesia. Hypertension and diabetes mellitus were the larger risk factors for COVID-19 mortality. Guo et al. 2020 found comorbid COVID-19 sufferers were hypertension 24.7% and diabetes mellitus 21.2%. However, Mikami et al., 2020 stated differently that hypertension and diabetes mellitus were not at risk of COVID-19 mortality. AIM: Objective of this study was to estimate the average tendency of hypertension and diabetes mellitus as risk factor for COVID-19 mortality. METHODS: Meta-analysis with 16 articles analyzed by RevMan 5.4.RESULTS: pHR for hypertension was 1.15 (95% CI 1.00 - 1.32) and diabetes mellitus was 1.21 (95% CI 1.13 - 1.29). CONCLUSION: Hypertension had risk 1.15 times and diabetes mellitus had risk 1.21 times for COVID-19 mortality.