Repo Dosen ULM

Antioxidant and Cytotoxicity Activities of Karamunting (Melastoma malabathricum L.) Fruit Ethanolic Extract and Quercetin

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dc.contributor.author Isnaini, Isnaini
dc.contributor.author Yasmina, Alfi
dc.contributor.author Wana Nur’amin, Hendra
dc.date.accessioned 2022-08-04T09:06:54Z
dc.date.available 2022-08-04T09:06:54Z
dc.date.issued 2018-05
dc.identifier.issn 2476-762
dc.identifier.uri https://repo-dosen.ulm.ac.id//handle/123456789/24991
dc.description.abstract Melastoma malabathricum L. is a type of plant naturally grows in Kalimantan that has medicinal properties. Ethanolic extract of M. malabathricum L. flower has quercetin and kaempferol contents that have antioxidant and anticancer activities. But the antioxidant and cytotoxicity activities of M. malabathricum L. fruit ethanolic extract were not known. This study measured the quercetin and kaempferol level in M. malabathricum L. fruit ethanolic extract using HPLC MS/MS, antioxidant activity using DPPH method, and cytotoxicity activity using Brine Shrimp Lethality Test (BSLT) method. Results showed the level of quercetin and kaempferol from M. malabathricum L fruit ethanolic extract are 67.78 μg/g and 43.52 μg/g, respectively. Beside, the antioxidant activity with by IC50 was 16.82±0.24 ppm and 7.38±0.41 ppm. The cytotoxicity activities of M. malabathricum L. fruit ethanolic extract and quercetin are shown by the LC50 of 313.44 ppm (95%CI 283.97-344.43) and 37.24 ppm, respectively. en_US
dc.publisher The Asian Pasific Journal of Cancer Prevantion (APJC)P en_US
dc.subject M. malabathricum L en_US
dc.subject quercetin en_US
dc.subject kaempferol en_US
dc.subject antioxidant en_US
dc.subject cytotoxicity en_US
dc.title Antioxidant and Cytotoxicity Activities of Karamunting (Melastoma malabathricum L.) Fruit Ethanolic Extract and Quercetin en_US
dc.title.alternative Antioxidant and Cytotoxicity Activities of Karamunting (Melastoma malabathricum L.) Fruit Ethanolic Extract and Quercetin en_US
dc.type Other en_US


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