Abstract:
Abstract
Burns are unique because they involve much dead tissue (eschar), which remain in place for an extended period. Salam
leaves can be used for wound treatment by attaching them to the wound place. One of the ingredients of Salam leaves is
an anti-bacterial which can kill and inhibit the growth of bacteria and antioxidants. This study aimed to determine the
activity of Salam leaf extract gel as a healing grade 2 burns in white rats.
Posttest Only Control Group Design used experimental white mice (Rattusnorvegicus strain Wistar). The sampling
technique was simple random sampling, consisting of 4 groups, namely 3 treatment groups giving salam leaf extract gel
each 15%, 30 and 40 %, 1 negative control group with standard saline solution 0.9%. Microscopic observation of the
thickness of the granulation tissue in the Hematoxylin-Eosin preparation was carried out. Data were analyzed using
descriptive analysis, data normality test with Shapiro Wilk, Kruskal Wallis comparison test.
Average grade 2 burns healing using salam leaf extract gel (Syzygiumpolyanthum) in experimental animals with 15% gel
was 3.3 days, 30% gel was 7.8 days, and 45% gel was 13 days, while with NaCl 0.9% is 12.7 days. The Kruskal-Wallis test
results show the Asymp value. Sig <0.05 indicates a difference between the administration of salam leaf extract and the
duration of healing burns. Histological examination in the bay leaf extract gel group's of 15% and 30% concentrations
showed the thickest granulation tissue thickness compared to other treatment groups.
Giving salam leaf extract gel is effective in the healing process of grade 2 burns. Further research is needed regarding the
treatment of burns grade 2 B or grade 3 and other various dosage forms and additional research on the standardization of
active ingredients that can be used as complementary or an alternative in the treatment of grade 2 burns for multiple
groups of people.
Abstract
Burns are unique in that they involve large amounts of dead tissue (eschars) that remain in place for long periods. Bay
leaves can be used for wound treatment by attaching them to the wound. One of the contents of bay leaves is an antibacterial that can kill and inhibit the growth of bacteria and antioxidants. This study aimed to determine the activity of the
extract gel bay leaf as a healer for grade 2 burns in white rats.
Method: True experimental research design with Posttest Only Control Group Design using experimental white rats
(Rattusnorvegicus strain Wistar), the sampling technique is simple random sampling, consisting of 4 groups, namely 3 the
