Hubungan Jumlah Leukosit dan C-Reactive Protein (CRP) dengan Luaran Pasien Cedera Otak Traumatik (COT) berdasarkan Skor Glasgow Coma Scale (GCS) di RSUD Ulin Banjarmasin

Abstract

Background and Objective: The severity of traumatic brain injury (TBI) can be assessed using the Glasgow Coma Scale (GCS). When head injury occurs, the body releases various inflammatory mediators, leukocytes and inflammatory markers, namely c-reactive protein (CRP). The purpose of this study was to determine whether there is a correlation between the leukocyte count and CRP levels with the outcome of TBI patients based on GCS scores in Ulin Hospital Banjarmasin. Subject and Method: This research is an analytic observational with cross-sectional approach. Data acquired with consecutive sampling method. Result: We Obtained 45 subjects with the highest mean of leukocytes count and the highest CRP levels in patients with severe TBI followed by moderate TBI and mild TBI. On the 7th day, 41 patients had good outcome and 4 patients had bad outcome. Analysis using the Spearman correlation test showed that there was a relationship between the leukocyte count (p = 0.004; r = 0.424) and CRP levels with the outcome of TBI patients (p = 0.043; r = 0.361). Conclusion: It was concluded that there is a correlation between leukocyte count and CRP levels with the outcome of TBI patients based on GCS scores Key words: CRP, GCS score, leukocyte count, traumatic brain injury