Repo Dosen ULM

The Effect of Cadmium Absorption on Ghrelin and Malondialdehyde Levels in White Rats (Rattusnorvegicus)

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dc.contributor.author Triawanti, Triawanti
dc.contributor.author Dwi Sanyoto, Didik
dc.contributor.author Mashuri, Mashuri
dc.contributor.author Wana Nur’amin, Hendra
dc.date.accessioned 2020-09-01T02:00:26Z
dc.date.available 2020-09-01T02:00:26Z
dc.date.issued 2014-07-02
dc.identifier.other DOI: 10.7763/IJBBB.2014.V4.351
dc.identifier.uri https://repo-dosen.ulm.ac.id//handle/123456789/17714
dc.description.abstract Abstract—Cadmium is expected to affect the absorption of other nutrients and appetite through the competition with the nutrients, causing damages to cell membranes through lipid peroxidation reactions. Damaged intestinal cells may disrupt the secretion of one of digestive hormones, ghrelin, theorexigenic hormone. The purpose of this study was to analyze the effect of cadmium exposure on the levels of ghrelin and malondialdehyde (MDA) in rats (Rattusnorvegicus). The study used post-test-only control group design, with 2 groups of white rats: control group (P0) was given placebo and treatment group (P1) was exposed to cadmium. Parameters measured were the levels of MDA and ghrelin. The results showed that there was no difference in body weights (p=0.057) and ghrelin concentrations (p=0.910) between the white rats in the control group and the treatment group. There were significant differences in the levels of MDA. The treatment group had a higher MDA level compared with control (p=0.001). It was concluded that the cadmium exposure for 4 group did not affect the secretion of ghrelin hormone and body weights of white rats, but might cause lipid peroxidation in white rats, as evidenced by the increased MDA level. en_US
dc.description.sponsorship Hibah FK ULM en_US
dc.language.iso en en_US
dc.publisher International Journal of Bioscience, Biochemistry and Bioinformatics en_US
dc.subject Cadmium, ghrelin, MDA, body weight. en_US
dc.title The Effect of Cadmium Absorption on Ghrelin and Malondialdehyde Levels in White Rats (Rattusnorvegicus) en_US
dc.type Article en_US


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