Abstract:
After being infected with A. hydrophila bacteria, haruan snakehead fish made efforts to
restore their condition through recovery. The secondary metabolites found in kelakai leaves,
namely alkaloid compounds, steroids, flavonoids, and iron, are believed to act as bloodboosting supplements. This study aims to analyze the histological response of the liver
organs of haruan snakehead fish after being infected with A. hydrophila bacteria and fed with
kelakai extract. The treatments provided for recovery were as follows: Treatment A (Control),
Treatment B (50ml/kg Kelakai Extract), Treatment C (100ml/kg Kelakai Extract), and
Treatment D (150ml/kg Kelakai Extract). The histological response of the liver organs of
haruan snakehead fish with the addition of kelakai extract has been shown to effectively
improve the histological structure of the liver post-infection with A. hydrophila bacteria, as
indicated by an increase in the number of melanomacrophages.